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Galanin Protein (GAL) (Fc Tag)

GAL Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7317568
  • Target Alle Galanin (GAL) Proteine anzeigen
    Galanin (GAL)
    Protein-Typ
    Recombinant
    Spezies
    • 3
    • 2
    • 1
    Human
    Quelle
    • 5
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Galanin Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human Galanin/GAL Protein (Fc Tag)
    Sequenz
    Met 1-Ser123
    Produktmerkmale
    A DNA sequence encoding the human GAL (P22466) (Met1-Ser123) was expressed with the Fc region of human IgG1 at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product GAL Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from sterile PBS, pH 7.4
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Galanin (GAL)
    Andere Bezeichnung
    Galanin/GAL (GAL Produkte)
    Synonyme
    Galn Protein, galanin and GMAP prepropeptide Protein, galanin Protein, GAL Protein, Gal Protein
    Hintergrund

    Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD180, also known as RP105, is a B-cell surface molecule belonging to the family of pathogen receptors, Toll-like receptors (TLR). CD180 has an extracellular leucine-rich repeats and a short cytoplasmic tail. CD180 / RP105 interact with an extracellular molecule named MD1 and then together form the cell surface receptor complex RP105 / MD1 which induces B-cell activation in humans and mice, leading to proliferation and up-regulation of a costimulatory molecule, B7.2 / CD86. CD180 / RP105 also has a role in LPS response because B cells lacking RP105 show hyporesponsiveness to LPS.

    Synonym: GAL-GMAP,GALN,GLNN,GMAP

    Molekulargewicht
    38.5 kDa
    UniProt
    P22466
    Pathways
    Regulation of Hormone Metabolic Process, Feeding Behaviour
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