GZMB Protein (His tag)
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- Target Alle GZMB Proteine anzeigen
- GZMB (Granzyme B (GZMB))
- Protein-Typ
- Recombinant
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Spezies
- Maus
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Quelle
- Human Cells
- Aufreinigungstag / Konjugat
- Dieses GZMB Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Mouse Granzyme B(G,H)/GZMB Protein (His Tag)
- Sequenz
- Gly19-Ser247
- Produktmerkmale
- Recombinant Mouse Granzyme B is produced by our Mammalian expression system and the target gene encoding Gly19-Ser247 is expressed with a 6His tag at the C-terminus.
- Reinheit
- > 85 % as determined by SDS-PAGE
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
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Granzyme B (GZMB) (AA 148-247) protein (GST tag)
GZMB Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme B (GZMB) (AA 21-247) protein (GST tag)GZMB Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme B (GZMB) (AA 1-247) protein (GST tag)GZMB Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- GZMB (Granzyme B (GZMB))
- Andere Bezeichnung
- Granzyme B/GZMB (GZMB Produkte)
- Hintergrund
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Background: Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Synonym: Granzyme B(G,H),CTLA-1,Cytotoxic cell protease 1,CCP1,Fragmentin-2,Gzmb,Ctla-1, Ctla1
- Molekulargewicht
- 26.5 kDa
- UniProt
- P04187
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose
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