GDF11 Protein

Produktnummer ABIN7318551

Produktdetails

Target: GDF11 (Growth Differentiation Factor 11 (GDF11))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Verwendungszweck: Recombinant Human GDF11/BMP-11 Protein

Sequenz: Asn299-Ser407

Produktmerkmale: Recombinant Human Growth differentiation factor 11 is produced by our Mammalian expression system and the target gene encoding Asn299-Ser407 is expressed.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: GDF11 (Growth Differentiation Factor 11 (GDF11))

Andere Bezeichnung: GDF11/BMP-11 (GDF11 Produkte)

Synonyme: BMP-11 Protein, BMP11 Protein, Bmp11 Protein, GDF11 Protein, growth differentiation factor 11 Protein, GDF11 Protein, Gdf11 Protein, gdf11 Protein

Hintergrund:

Background: Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The similarities between GDF11 and myostatin imply a likelihood that the same regulatory mechanisms are used to control tissue size during both muscular and neural development.

Synonym: Growth/differentiation factor 11,GDF-11,Bone morphogenetic protein 11,BMP-11

Molekulargewicht: 12.6 kDa

UniProt: O95390