Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

GAMT Protein (His tag)

GAMT Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318555
  • Target Alle GAMT Proteine anzeigen
    GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
    Protein-Typ
    Recombinant
    Spezies
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 6
    • 5
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses GAMT Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human GAMT Protein (His Tag)
    Sequenz
    Met 1-Gly236
    Produktmerkmale
    Recombinant Human Guanidinoacetate N-methyltransferase is produced by our E.coli expression system and the target gene encoding Met1-Gly236 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product GAMT Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,1 mMDTT, pH 8.0 .
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
    Andere Bezeichnung
    GAMT (GAMT Produkte)
    Synonyme
    gamt Protein, zgc:123136 Protein, CCDS2 Protein, PIG2 Protein, TP53I2 Protein, AA571402 Protein, Spintz1 Protein, MGC75698 Protein, GAMT Protein, GMT Protein, guanidinoacetate N-methyltransferase L homeolog Protein, guanidinoacetate N-methyltransferase S homeolog Protein, guanidinoacetate N-methyltransferase Protein, guanidinoacetate methyltransferase Protein, gamt.L Protein, gamt.S Protein, gamt Protein, GAMT Protein, Gamt Protein
    Hintergrund

    Background: GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily. It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver. GAMT converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in GAMT are the cause of guanidinoacetate methyltransferase deficiency, which is an autosomal recessive disorder characterized by developmental delay/regression, mental retardation, severe disturbance of expressive and cognitive speech, intractable seizures and movement disturbances, severe depletion of creatine/phosphocreatine in the brain, and accumulation of guanidinoacetic acid in brain and body fluids.

    Synonym: Guanidinoacetate N-methyltransferase, GAMT, PIG2,TP53I2

    Molekulargewicht
    29.5 kDa
    UniProt
    Q14353
Sie sind hier:
Kundenservice