HYAL1 Protein (His tag)
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- Target Alle HYAL1 Proteine anzeigen
- HYAL1 (Hyaluronidase-1 (HYAL1))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Human Cells
- Aufreinigungstag / Konjugat
- Dieses HYAL1 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human Hyaluronidase-1/HYAL1 Protein (His Tag)
- Sequenz
- Phe22-Trp435
- Produktmerkmale
- Recombinant Human Hyaluronidase-1 is produced by our Mammalian expression system and the target gene encoding Phe22-Trp435 is expressed with a 6His tag at the C-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product HYAL1 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 7.5.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- HYAL1 (Hyaluronidase-1 (HYAL1))
- Andere Bezeichnung
- Hyaluronidase-1/HYAL1 (HYAL1 Produkte)
- Synonyme
- HYAL-1 Protein, LUCA1 Protein, NAT6 Protein, Hya1 Protein, Hyal-1 Protein, hyaluronoglucosaminidase 1 Protein, HYAL1 Protein, Hyal1 Protein
- Hintergrund
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Background: Hyaluronidase-1 (HYAL1) is a secreted lysosomal hyaluronidase that belongs to the glycosyl hydrolase 56 family. HYAL1 contains one EGF-like domain and is highly expressed in the liver, kidney, and heart, but it is weakly expressed in the lung, placenta, and skeletal muscle. HYAL1 is thought to be involved in cell proliferation, migration, and differentiation. It may play a role in promoting tumor progression and blocking the TGFB1-enhanced cell growth. Mutations in HYAL1 are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.
Synonym: Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1, Lung Carcinoma Protein 1, LuCa-1, HYAL1, LUCA1
- Molekulargewicht
- 47.2 kDa
- UniProt
- Q12794
- Pathways
- Glycosaminoglycan Metabolic Process
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