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IL-11 Protein

IL11 Spezies: Human Wirt: Yeast (Pichia pastoris) Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7319568
  • Target Alle IL-11 (IL11) Proteine anzeigen
    IL-11 (IL11) (Interleukin 11 (IL11))
    Protein-Typ
    Recombinant
    Spezies
    • 13
    • 8
    • 2
    • 2
    Human
    Quelle
    • 9
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Yeast (Pichia pastoris)
    Verwendungszweck
    Recombinant Human Interleukin-11/IL-11 Protein
    Sequenz
    Gly23-Leu199
    Produktmerkmale
    Recombinant Human Interleukin-11 is produced by our Yeast expression system and the target gene encoding Gly23-Leu199 is expressed.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IL11 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 2 % Glycine, pH 7.2.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    IL-11 (IL11) (Interleukin 11 (IL11))
    Andere Bezeichnung
    Interleukin-11/IL-11 (IL11 Produkte)
    Synonyme
    IL11 Protein, AGIF Protein, IL-11 Protein, Il-11 Protein, interleukin 11 Protein, IL11 Protein, Il11 Protein
    Hintergrund

    Background: Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. IL-11 is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2, It activates a signaling cascade that promotes cell proliferation. The signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

    Synonym: Interleukin-11, IL-11, Adipogenesis Inhibitory Factor, AGIF, Oprelvekin, IL11

    Molekulargewicht
    19 kDa
    UniProt
    P20809
    Pathways
    JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
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