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IL23 Protein (Fc Tag)

IL23 Spezies: Human Wirt: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7319788
  • Target Alle IL23 Proteine anzeigen
    IL23 (Interleukin 23 (IL23))
    Protein-Typ
    Recombinant
    Spezies
    • 5
    • 5
    • 1
    Human
    Quelle
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses IL23 Protein ist gelabelt mit Fc Tag.
    Verwendungszweck
    Recombinant Human Interleukin-23/IL-23 (C-Fc)
    Sequenz
    Ile23-Ser328&Ala21-Pro189
    Produktmerkmale
    Recombinant Human Interleukin-23 is produced by our Mammalian expression system and the target gene encoding Ile23-Ser328&Ala21-Pro189 is expressed with a Fc tag at the C-terminus.
    Reinheit
    >95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IL23 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    IL23 (Interleukin 23 (IL23))
    Andere Bezeichnung
    Interleukin-23/IL-23 (IL23 Produkte)
    Synonyme
    IL-23 Protein, p19 Protein, SGRF Protein, il23p19 Protein, interleukin 23, alpha subunit p19 Protein, interleukin 23 subunit alpha Protein, Il23a Protein, IL23A Protein
    Hintergrund

    Background: Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12, as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. Although p19 is expressed by activated macrophages, dendritic cells, T cells, and endothelial cells, only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. IL-23 has biological activities that are similar to, but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human T cells, the effects of IL-23 is restricted to memory T cells.

    Synonym: SGRF, IL-23p19, CLMF p40, IL-12 subunit p40, NKSF2

    Molekulargewicht
    81.3 kDa
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