IL3RA Protein (Fc Tag)
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- Target Alle IL3RA Proteine anzeigen
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- Protein-Typ
- Recombinant
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Spezies
- Cynomolgus
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Quelle
- Human Cells
- Aufreinigungstag / Konjugat
- Dieses IL3RA Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Recombinant Cynomolgus IL-3 Receptor Subunit Alpha/IL-3RA/CD123 (C-Fc)
- Sequenz
- Arg18-Arg302
- Produktmerkmale
- Recombinant Cynomolgus Interleukin-3 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Arg18-Arg302 is expressed with a 6His tag at the C-terminus.
- Reinheit
- >95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product IL3RA Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- Andere Bezeichnung
- IL-3 Receptor Subunit Alpha/IL-3RA/CD123 (IL3RA Produkte)
- Synonyme
- CD123 Protein, IL3R Protein, IL3RAY Protein, IL3RX Protein, IL3RY Protein, hIL-3Ra Protein, CDw123 Protein, SUT-1 Protein, Cyrl Protein, interleukin 3 receptor subunit alpha Protein, interleukin 3 receptor, alpha chain Protein, IL3RA Protein, Il3ra Protein
- Hintergrund
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Background: CD123, also known as Interleukin-3 receptor subunit alpha, belongs to the type I cytokine receptor family. In mouse, there are two classes of high-affinity IL3 receptors. One contains an IL3-specific beta subunit and the other contains the beta subunit also shared by high-affinity IL5 and GM-CSF receptors. CD123 stimulates the proliferation and differentiation of hemopoietic cells including the pluripotent hematopoietic stem cells as well as various lineage-committed cells. CD123 is a heterodimer consisting of an alpha and a beta subunit. The alpha subunit alone binds IL-3 with low affinity. The beta subunit does not bind IL-3 by itself but is required for the high-affinity binding of IL-3 to the heterodimeric receptor complex.
Synonym: Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, CD123
- Molekulargewicht
- 33.6 kDa
- UniProt
- G8F3K3
- Pathways
- JAK-STAT Signalweg
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