IL4 Receptor Protein (His tag)
-
- Target Alle IL4 Receptor (IL4R) Proteine anzeigen
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
-
Spezies
- Ratte
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses IL4 Receptor Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Rat IL4RA/CD124 Protein (His Tag)(Active)
- Sequenz
- Met1-Arg232
- Produktmerkmale
- A DNA sequence encoding the rat IL4R (Q63257-1) (Met1-Arg232) was expressed, fused with a polyhistidine tag at the C-terminus.
- Reinheit
- > 95 % as determined by SDS-PAGE
- Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method
- Biological Activity Comment
- Measured by its ability to bind biotinylated mouse IL4-His in a functional ELISA.
- Top Product
- Discover our top product IL4R Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- Andere Bezeichnung
- IL4RA/CD124 (IL4R Produkte)
- Synonyme
- IL4R Protein, il-4ra Protein, zgc:113063 Protein, CD124 Protein, IL-4RA Protein, IL4RA Protein, Il4ra Protein, IL4 Protein, Il4r Protein, interleukin 4 receptor Protein, interleukin 4 receptor, tandem duplicate 1 Protein, interleukin 4 receptor, alpha Protein, IL4R Protein, il4r.1 Protein, Il4r Protein, Il4ra Protein
- Hintergrund
-
Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD124, also known as interleukin 4 receptor (IL4R), is a typeI transmembrane protein that can regulate IgE antibody production in B cells through binding to interleukin 4 and interleukin 13 and promote differentiation of Th2 cells through binding to interleukin 4. The membrane-bound form of CD124 can be hydrolyzed to soluble form which can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells.
Synonym: IL4R,Il4ra
- Molekulargewicht
- 25.3 kDa
- Pathways
- JAK-STAT Signalweg, Positive Regulation of Immune Effector Process
-