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Kallikrein 2 Protein (KLK2) (His tag)

KLK2 Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318697
  • Target Alle Kallikrein 2 (KLK2) Proteine anzeigen
    Kallikrein 2 (KLK2)
    Protein-Typ
    Recombinant
    Spezies
    • 7
    • 1
    • 1
    Human
    Quelle
    • 3
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses Kallikrein 2 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Kallikrein 2/KLK2 Protein (His Tag)
    Sequenz
    Pro19-Pro261
    Produktmerkmale
    Recombinant Human Kallikrein 2 is produced by our Mammalian expression system and the target gene encoding Pro19-Pro261 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product KLK2 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Citrate, 150 mM NaCl, pH 3.5.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    Kallikrein 2 (KLK2)
    Andere Bezeichnung
    Kallikrein 2/KLK2 (KLK2 Produkte)
    Synonyme
    KLK2A2 Protein, hGK-1 Protein, hK2 Protein, KLK2 Protein, Ton Protein, rGK-2 Protein, Klk2 Protein, kallikrein related peptidase 2 Protein, kallikrein-related peptidase 2 Protein, kallikrein-2 Protein, kallikrein 1-related peptidase C2 Protein, KLK2 Protein, LOC748637 Protein, Klk1c2 Protein, LOC100716976 Protein
    Hintergrund

    Background: Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa. KLK2 is inhibited by serpins such as protein C inhibitor, antichymotrypsin, and plasminogen. KLK2 is considered to be a biomarker for prostate cancer.

    Synonym: Kallikrein-2, Glandular Kallikrein-1, hGK-1, Tissue Kallikrein-2, KLK2

    Molekulargewicht
    27.9 kDa
    UniProt
    P20151
    Pathways
    Komplementsystem
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