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LUM Protein (His tag)

LUM Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318743
  • Target Alle LUM Proteine anzeigen
    LUM (Lumican (LUM))
    Protein-Typ
    Recombinant
    Spezies
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses LUM Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Lumican/LUM Protein (His Tag)
    Sequenz
    Gln19-Asn338
    Produktmerkmale
    Recombinant Human Lumican is produced by our Mammalian expression system and the target gene encoding Gln19-Asn338 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product LUM Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.2.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    LUM (Lumican (LUM))
    Andere Bezeichnung
    Lumican/LUM (LUM Produkte)
    Synonyme
    MGC64527 Protein, zgc:86661 Protein, ldc Protein, slrr2d Protein, DKFZp468L1116 Protein, LDC Protein, SLRR2D Protein, Ldc Protein, lumican Protein, lumican L homeolog Protein, LUM Protein, lum.L Protein, lum Protein, CpipJ_CPIJ010209 Protein, Lum Protein
    Hintergrund

    Background: Lumican is a 40 kD secreted protein which belongs to the small leucine-rich repeat proteoglycans (SLRPs) and the class II subfamily. Human Lumican is synthesized as a 338 amino acid precursor then cut the 18 aa signal sequence. The mature Human Lumican contains 12 leucine-rich repeats (LRRs), 4 potential sites of N-linked glycosylation, and a C- terminal with two conserved cyst-eines. Lumican can be existed in extracellular matrix of human articular cartilage. Lumican participates in the maintenance of tissue homeostasis and regulates cellular functions in vivo, such as cell proliferation, adhesion, migration, and differentiation. The overexpression of lumican has been correlated to colorectal tumor, breast, neuroendocrine, and pancreatic cancers.

    Synonym: Lumican, Keratan Sulfate Proteoglycan Lumican, KSPG Lumican, LUM, LDC, SLRR2D

    Molekulargewicht
    37.7 kDa
    UniProt
    P51884
    Pathways
    Glycosaminoglycan Metabolic Process
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