SGSH Protein (His tag)
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- Target Alle SGSH Proteine anzeigen
- SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Human Cells
- Aufreinigungstag / Konjugat
- Dieses SGSH Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human SGSH Protein (His Tag)
- Sequenz
- Arg21-Leu502
- Produktmerkmale
- Recombinant Human N-Sulphoglucosamine Sulphohydrolase is produced by our Mammalian expression system and the target gene encoding Arg21-Leu502 is expressed with a 6His tag at the C-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SGSH Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM GaCl2,10 % Glycerol, pH 7.5.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))
- Andere Bezeichnung
- SGSH (SGSH Produkte)
- Hintergrund
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Background: N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.
Synonym: N-Sulphoglucosamine Sulphohydrolase, Sulfoglucosamine Sulfamidase, Sulphamidase, SGSH, HSS
- Molekulargewicht
- 55.7 kDa
- UniProt
- P51688
- Pathways
- Glycosaminoglycan Metabolic Process
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