Neuroligin 4 Protein (NLGN4) (His tag)

Produktnummer ABIN7318817

Produktdetails

Target: Neuroligin 4 (NLGN4)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses Neuroligin 4 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human NLGN4X Protein (His Tag)

Sequenz: Gln42-Ser676

Produktmerkmale: Recombinant Human Neuroligin 4, X-Linked is produced by our Mammalian expression system and the target gene encoding Gln42-Ser676 is expressed with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Neuroligin 4 (NLGN4)

Andere Bezeichnung: NLGN4X (NLGN4 Produkte)

Synonyme: ASPGX2 Protein, AUTSX2 Protein, HLNX Protein, HNL4X Protein, NLGN4 Protein, nlgn4 Protein, NLGN4X Protein, Nlgn4x Protein, neuroligin 4, X-linked Protein, neuroligin-4, X-linked Protein, NLGN4X Protein, nlgn4x Protein, LOC100714631 Protein

Hintergrund:

Background: Neuroligin 4, X-Linked (NLGN4X) is a single-pass type I membrane protein that belongs to the type-B carboxylesterase/lipase family. NLGN4X is detected at higher levels in heart and at lower levels in the liver, skeletal muscle, and pancreas. NLGN4X is a putative neuronal cell surface protein involved in cell-cell-interactions. NLGN4X may act as splice site-specific ligands for β-neurexins. It has been shown that NLGN4X is involved in the formation and remodeling of central nervous system synapses. NLGN4X also interacts with discs, large (Drosophila) homolog 4 (DLG4). Defects in NLGN4X have been associated with autism and Asperger syndrome.

Synonym: Neuroligin-4 X-Linked, Neuroligin X, HNLX, NLGN4X, KIAA1260, NLGN4

Molekulargewicht: 72.5 kDa

UniProt: Q8N0W4

Pathways: Cell-Cell Junction Organization, Synaptic Membrane