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NPTN Protein (His tag)

NPTN Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318820
  • Target Alle NPTN Proteine anzeigen
    NPTN (Neuroplastin (NPTN))
    Protein-Typ
    Recombinant
    Spezies
    • 4
    • 1
    Human
    Quelle
    • 2
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses NPTN Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Neuroplastin/NPTN Protein (His Tag)
    Sequenz
    Gln29-His220
    Produktmerkmale
    Recombinant Human Neuroplastin is produced by our Mammalian expression system and the target gene encoding Gln29-His220 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product NPTN Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    NPTN (Neuroplastin (NPTN))
    Andere Bezeichnung
    Neuroplastin/NPTN (NPTN Produkte)
    Synonyme
    SDFR1 Protein, GP55 Protein, GP65 Protein, SDR1 Protein, np55 Protein, np65 Protein, AW554172 Protein, Sdfr1 Protein, nptn Protein, zgc:77326 Protein, neuroplastin Protein, neuroplastin L homeolog Protein, neuroplastin b Protein, NPTN Protein, Nptn Protein, nptn.L Protein, nptnb Protein
    Hintergrund

    Background: Neuroplastin (NPTN) is a 52-57 kDa member of the Ig-superfamily. Neuroplastin likely serves as a cell adhesion molecule, and is widely expressed in multiple tissues. Human Neuroplastin is 282 amino acids that contions two Ig-like domains and a 38 aa cytoplasmic region. Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. Neuroplastin may also regulate neurite outgrowth by activating the FGFR1 signaling pathway. It may play a role in synaptic plasticity.

    Synonym: Neuroplastin, Stromal Cell-Derived Receptor 1, SDR-1, NPTN, SDFR1, SDR1

    Molekulargewicht
    22.7 kDa
    UniProt
    Q9Y639
    Pathways
    Regulation of long-term Neuronal Synaptic Plasticity
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