PPIA Protein (His tag)

Produktnummer ABIN7197305

Produktdetails

Target: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PPIA Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse Cyclophilin A Protein (His Tag)

Sequenz: Met 1-Leu 164

Produktmerkmale: A DNA sequence encoding the mouse PPIA (NP_032933.1) (Met 1-Leu 164) was expressed, with a polyhistide tag at the C-terminus.

Reinheit: > 97 % as determined by SDS-PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4, 10 % glycerol

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))

Andere Bezeichnung: Cyclophilin A (PPIA Produkte)

Hintergrund:

Background: Peptidyl-prolyl cis-trans isomerase A, also known as PPIase A, Rotamase A, Cyclophilin A, Cyclosporin A-binding protein, PPIA and CYPA, is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins (CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity, suggesting that they influence the conformation of proteins in cells. PPIA / Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA / Cyclophilin A is secreted by vascular smooth muscle cells in response to inflammatory stimuli, and could thus contribute to atherosclerosis. It is not essential for mammalian cell viability. PPIA / Cyclophilin A can interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.

Synonym: 2700098C05 Protein, Mouse;Cphn Protein, Mouse;CyP-18 Protein, Mouse;CypA Protein, Mouse

Molekulargewicht: 18.8 kDa

NCBI Accession: NP_032933