Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Persephin Protein (PSPN) (His tag)

PSPN Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7319503
  • Target Alle Persephin (PSPN) Proteine anzeigen
    Persephin (PSPN)
    Protein-Typ
    Recombinant
    Spezies
    • 4
    • 3
    • 1
    Human
    Quelle
    • 7
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses Persephin Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Persephin/PSPN Protein (His Tag)
    Sequenz
    Ala61-Gly156
    Produktmerkmale
    Recombinant Human Persephin is produced by our E.coli expression system and the target gene encoding Ala61-Gly156 is expressed.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PSPN Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Persephin (PSPN)
    Andere Bezeichnung
    Persephin/PSPN (PSPN Produkte)
    Synonyme
    PSPN Protein, PSP Protein, persephin Protein, PSPN Protein, Pspn Protein
    Hintergrund

    Background: Persephin is a secreted protein, belongs to the glial cell linederived neurotrophic factor (GDNF) family of the TGF-β superfamily. It shares 38-46 % amino acid (aa) identity with family members GDNF, neurturin and artemin. It is expressed at very low levels in most tissues. Mature protein contains a signal sequence, a pro-domain and a 96 aa mature sequence with several cysteines that are conserved among family members. It circulates as an unglycosylated disulfide-linked homodimer. Like other GDNF family members, Persephin acts through engagement of GRFα4, a glycosylphosphatidylinositol (GPI)-linked GDNF receptor family Persephin is reported to promote both the survival and growth of central dopaminergic and motor neurons, and kidney development. These effects are correlated with the expression patterns of GFRα4, and RET.

    Synonym: Persephin, PSP, PSPN

    Molekulargewicht
    10.4 kDa
    UniProt
    O60542
Sie sind hier:
Kundenservice