Pleiotrophin Protein (PTN) (His tag)
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- Target Alle Pleiotrophin (PTN) Proteine anzeigen
- Pleiotrophin (PTN)
- Protein-Typ
- Recombinant
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Spezies
- Maus
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Quelle
- Human Cells
- Aufreinigungstag / Konjugat
- Dieses Pleiotrophin Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Mouse Pleiotrophin/PTN/HB-GAM Protein (His Tag)
- Sequenz
- Gly33-Asp168
- Produktmerkmale
- Recombinant Mouse Pleiotrophin is produced by our Mammalian expression system and the target gene encoding Gly33-Asp168 is expressed with a 6His tag at the C-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PTN Protein
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Pleiotrophin (PTN) (AA 33-168) protein (Fc Tag)
PTN Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Pleiotrophin (PTN) (AA 1-168) protein (GST tag)PTN Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Pleiotrophin (PTN) (AA 33-168) protein (Fc Tag)PTN Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
Pleiotrophin (PTN) (Active) proteinPTN Spezies: Maus Wirt: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE Active
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- Pleiotrophin (PTN)
- Andere Bezeichnung
- Pleiotrophin/PTN/HB-GAM (PTN Produkte)
- Hintergrund
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Background: Pleiotrophin (PTN) is an secreted, strongly heparinbinding,developmentally regulated cytokine. PTN and midkine share50 % amino acid (aa) sequence identity, share some functions, and constitute a family. PTN is a highly conserved protein? human, mouse, rat, canine, porcine, equine and bovine PTN share 98 % aa sequence identity orgreater. During development, PTN is involved in development of brain, bone, and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates its phosphatase activity, which allows increased tyrosine phosphorylation of its substrates. Increased expression of PTN is correlated withneuronal development or stresses such as brain ischemia and Parkinson's disease.
Synonym: Pleiotrophin, PTN, Heparin-binding brain mitogen, HBBM, Heparin-binding growth factor 8, HBGF-8, Osteoblast-specific factor 1, OSF-1,HARP,HB-GAM,HBBN,HBNF,OSF,Osf-1,Osf1
- Molekulargewicht
- 16.1 kDa
- UniProt
- P63089
- Pathways
- RTK Signalweg
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