PROS1 Protein (His tag)

Produktnummer ABIN7197584

Recombinant PROS1-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für PROS1 Protein (His tag) (ABIN7197584)

Target: PROS1 (PROS) (Protein S (PROS))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses PROS1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human PROS1/Protein S Protein (His Tag)

Sequenz: Met 1-Ser676

Produktmerkmale: A DNA sequence encoding the human PROS1 (P07225) (Met1-Ser676) was expressed with a polyhistidine tag at the C-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: PROS1 (PROS) (Protein S (PROS))

Andere Bezeichnung: PROS1

Hintergrund: PROS,PS21,PS22,PS23,PS24,PS25,PSA,Protein S,THPH5,THPH6,PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free, functionally active form and an inactive form complexed with C4b-binding protein. Besides its anticoagulant function, PROS1 also acts as an agonist for the tyrosine kinase receptors Tyro3, Axl, and Mer. The endothelium expresses Tyro3, Axl, and Mer and produces protein S. The interaction of protein S with endothelial cells and particularly its effects on angiogenesis have not yet been analyzed.

Molekulargewicht:

Calculated MW: 74.1 kDa

Observed MW: 69-89 kDa

Gen-ID: 5627

UniProt: P07225