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Proteoglycan 3 Protein (PRG3) (His tag)

PRG3 Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318966
  • Target Alle Proteoglycan 3 (PRG3) Proteine anzeigen
    Proteoglycan 3 (PRG3)
    Protein-Typ
    Recombinant
    Spezies
    Human
    Quelle
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses Proteoglycan 3 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Proteoglycan 3/PRG3 Protein (His Tag)
    Sequenz
    Leu18-Phe225
    Produktmerkmale
    Recombinant Human Proteoglycan 3 is produced by our Mammalian expression system and the target gene encoding Leu18-Phe225 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PRG3 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Proteoglycan 3 (PRG3)
    Andere Bezeichnung
    Proteoglycan 3/PRG3 (PRG3 Produkte)
    Synonyme
    MBP2 Protein, MBPH Protein, proteoglycan 3, pro eosinophil major basic protein 2 Protein, proteoglycan 3 Protein, PRG3 Protein, Prg3 Protein
    Hintergrund

    Background: Proteoglycan 3, also known as Eosinophil major basic protein homolog, Prepro-major basic protein homolog, PRG3 and MBPH, contains one C-type lectin domain. Proteoglycans are a major component of the animal extracellular matrix. PRG3 localizes to the eosinophil secondary granule and is expressed in bone marrow, not detected in placenta. PRG3 has similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, PRG3 can stimulate neutrophil superoxide production and IL8 release, histamine and leukotriene C4 release from basophils.

    Synonym: Proteoglycan 3, Eosinophil Major Basic Protein Homolog, Prepro-Major Basic Protein Homolog, Prepro-MBPH, PRG3, MBPH

    Molekulargewicht
    24.6 kDa
    UniProt
    Q9Y2Y8
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