RPS19 Protein

Produktnummer ABIN7318112

Produktdetails

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Verwendungszweck: Recombinant Human RPS19 Protein

Sequenz: Pro2-His145

Produktmerkmale: Recombinant Human 40S Ribosomal Protein S19 is produced by our E.coli expression system and the target gene encoding Pro2-His145 is expressed.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Andere Bezeichnung: RPS19 (RPS19 Produkte)

Synonyme: DBA Protein, DBA1 Protein, S19 Protein, Dsk3 Protein, 30S ribosomal protein S19 Protein, 40S ribosomal protein S19 Protein, ribosomal protein S19 Protein, rps19 Protein, rps-19 Protein, RPS19 Protein, Rps19 Protein

Hintergrund:

Background: 40S Ribosomal Protein S19 (RPS19) is a ribosomal protein that Belongs to the ribosomal protein S19e family. RPS19 is located in the nucleoli, and higher level expression is seen in colon carcinoma tissue than normal colon tissue. It required for pre-rRNA processing and maturation of 40S ribosomal subunits. RPS19 plays a role in many biological processes, such as endocrine pancreas development, erythrocyte differentiation, mRNA metabolic process. Defects in RPS19 are the cause of Diamond-Blackfan anemia type 1 (DBA1), which is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy.

Synonym: 40S Ribosomal Protein S19, RPS19

Molekulargewicht: 16.1 kDa

UniProt: P39019

Pathways: Positive Regulation of Immune Effector Process, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly