SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N)

Produktnummer ABIN7197805

Produktdetails

Target: SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: SARS Coronavirus-2 (SARS-CoV-2)

Quelle: Human Cells

Verwendungszweck: Recombinant SARS-CoV-2 Nucleocapsid Protein(Active)

Sequenz: Met1-Ala419

Produktmerkmale: Recombinant 2019-nCoV Nucleocapsid Protein is produced by our Mammalian expression system and the target gene encoding Met1-Ala419 is expressed with a 6His tag at the C-terminus.

Reinheit: Greater than 95 % as determined by reducing SDS-PAGE.

Biological Activity Comment: Immobilized 2019-nCoV NP Antibody(6G9)-Fc(Cat#DA027) at 5μg/ml(100 μl/well) can bind Recombinant 2019-nCoV Nucleocapsid Protein (Mammalian)-His(Cat#DRA91).The ED50 of 2019-nCoV Nucleocapsid Protein-His(Cat#DRA91) is 0.172 ug/ml.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCl, 150 mM NaCl, 50 mM Arginine, pH 7.5

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

Andere Bezeichnung: SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N Produkte)

Synonyme: nucleocapsid phosphoprotein Protein, N Protein

Substanzklasse: Viral Protein

Hintergrund:

Background: Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

Synonym: SARS-CoV-2 coronavirus NP Protein, SARS-CoV-2 np Protein, SARS-CoV-2 novel coronavirus Nucleoprotein Protein

Molekulargewicht: 46.4kDa