SELPLG Protein (His tag,Fc Tag)
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- Target Alle SELPLG Proteine anzeigen
- SELPLG (Selectin P Ligand (SELPLG))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses SELPLG Protein ist gelabelt mit His tag,Fc Tag.
- Verwendungszweck
- Recombinant Human PSGL-1/CD162 Protein (His & Fc Tag)
- Sequenz
- Met 1-Val295
- Produktmerkmale
- A DNA sequence encoding the extracellular domain (Met1-Val295) of human PSGL-1 precursor (AAC50061.1) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SELPLG Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- SELPLG (Selectin P Ligand (SELPLG))
- Andere Bezeichnung
- PSGL-1/CD162 (SELPLG Produkte)
- Synonyme
- CD162 Protein, CLA Protein, PSGL-1 Protein, PSGL1 Protein, SELPLG Protein, SELPG Protein, Psgl-1 Protein, Psgl1 Protein, Selp1 Protein, Selpl Protein, selectin P ligand Protein, selectin, platelet (p-selectin) ligand Protein, clasper Protein, SELPLG Protein, Selplg Protein, cla Protein
- Hintergrund
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Background: P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~120 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 protein requires two distinct posttranslational modifications for the Ca2+-dependent recognition by the lectin domain of P-selectin, that is tyrosine sulfation and specific O-linked glycosylation (sialic acid and fucose). PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.
Synonym: P-selectin glycoprotein ligand 1, PSGL-1, Selectin P ligand, CD162, SELPLG,CLA,PSGL1
- Molekulargewicht
- 57.1 kDa
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