SERPINB4 Protein (His tag)
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- Target Alle SERPINB4 Proteine anzeigen
- SERPINB4 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 4 (SERPINB4))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Baculovirus infected Insect Cells
- Aufreinigungstag / Konjugat
- Dieses SERPINB4 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human SerpinB4 Protein (His Tag)
- Sequenz
- Met 1-Pro 390
- Produktmerkmale
- A DNA sequence encoding the human SERPINB4 (P48594) (Met 1-Pro 390) was expressed, with a polyhistidine tag at the N-terminus.
- Reinheit
- > 88 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product SERPINB4 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 20 % glycerol, 1 mM EDTA, 1 mM DTT
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- SERPINB4 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 4 (SERPINB4))
- Andere Bezeichnung
- SerpinB4 (SERPINB4 Produkte)
- Synonyme
- LEUPIN Protein, PI11 Protein, SCCA-2 Protein, SCCA1 Protein, SCCA2 Protein, serpinb4 Protein, serpin family B member 4 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 4 L homeolog Protein, SERPINB4 Protein, serpinb4.L Protein
- Hintergrund
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Background: Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells. Uracil-DNA glycosylase exists in two forms: mitochondrial uracil-DNA glycosylase 1 (UNG1) and nuclear uracil-DNA glycosylase 2 (UNG2). uracil-DNA glycosylase. This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. Defects in UNG are a cause of immunodeficiency with hyper-IgM type 5 (HIGM5). A rare immunodeficiency syndrome characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE. It results in a profound susceptibility to bacterial infections.
Synonym: LEUPIN,PI11,SCCA-2,SCCA1,SCCA2
- Molekulargewicht
- 47.1 kDa
- UniProt
- P48594
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