TRIM Protein (His tag)
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- Target Alle TRIM (TRAT1) Proteine anzeigen
- TRIM (TRAT1) (T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses TRIM Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human TRIM/TRAT1 Protein (His Tag)
- Sequenz
- Asn29-Asn186
- Produktmerkmale
- Recombinant Human T Cell Receptor Interacting Molecule is produced by our E.coli expression system and the target gene encoding Asn29-Asn186 is expressed with a 6His tag at the C-terminus.
- Reinheit
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TRAT1 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,10 % Glycerol, pH 7.4.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- TRIM (TRAT1) (T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1))
- Andere Bezeichnung
- TRIM/TRAT1 (TRAT1 Produkte)
- Synonyme
- TCRIM Protein, TRIM Protein, C030046M14Rik Protein, Tcrim Protein, Trim Protein, T cell receptor associated transmembrane adaptor 1 Protein, T-cell receptor associated transmembrane adaptor 1 Protein, TRAT1 Protein, Trat1 Protein
- Hintergrund
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Background: T-Cell Receptor-Associated Transmembrane Adapter 1 (TRAT1) is a single-pass type III membrane protein. TRAT1 exists as a disulfide-linked homodimer and is strongly expressed in the thymus, and to a lesser extent in the spleen, lymph node, and peripheral blood lymphocytes. TRAT1 is phosphorylated on tyrosines by LCK or FYN upon TCR activation. Its function is to stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
Synonym: T-Cell Receptor-Associated Transmembrane Adapter 1, T-Cell Receptor-Interacting Molecule, TRIM, pp29/30, TRAT1, TCRIM, HSPC062
- Molekulargewicht
- 19.4 kDa
- UniProt
- Q6PIZ9
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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