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alpha Taxilin Protein (His tag)

TXLNA Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7319208
  • Target Alle alpha Taxilin (TXLNA) Proteine anzeigen
    alpha Taxilin (TXLNA) (Taxilin alpha (TXLNA))
    Protein-Typ
    Recombinant
    Spezies
    • 6
    • 1
    Human
    Quelle
    • 4
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses alpha Taxilin Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human TXLNA Protein (His Tag)
    Sequenz
    Met 1-Lys162
    Produktmerkmale
    Recombinant Human alpha-Taxilin is produced by our E.coli expression system and the target gene encoding Met1-Lys162 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TXLNA Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    alpha Taxilin (TXLNA) (Taxilin alpha (TXLNA))
    Andere Bezeichnung
    TXLNA (TXLNA Produkte)
    Hintergrund

    Background: α-Taxilin belongs to the taxilin family. α-Taxilin exists in almost all tissues, with higher expression levels observed in the heart, kidney, liver, and pancreas. α-Taxilin binds to the C-terminal coiled coil region of syntaxin family members STX1A, STX3A, and STX4A, but not when these proteins are complexed with SNAP25, VAMP2 or STXBP1, suggesting that it interacts with syntaxins that do not form the SNARE complex. It is shown that α-Taxilin plays multiple roles in the generation and maintenance of neurons through modulation of the NAC-mediated translational machinary and/or the syntaxin-mediated vesicle traffic in the soma. In addition, α-Taxilin may be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.

    Synonym: Alpha-Taxilin, TXLNA, TXLN

    Molekulargewicht
    20.4 kDa
    UniProt
    P40222
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