TPST1 Protein (His tag)
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- Target Alle TPST1 Proteine anzeigen
- TPST1 (Tyrosylprotein Sulfotransferase 1 (TPST1))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses TPST1 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Human TPST1 Protein (His Tag)
- Sequenz
- Gln 26-Glu 370
- Produktmerkmale
- A DNA sequence encoding the human TPST1 (NP_003587.1) extracellular domain (Gln 26-Glu 370) was expressed, with a polyhistidine tag at the N-terminus.
- Reinheit
- > 80 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TPST1 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- TPST1 (Tyrosylprotein Sulfotransferase 1 (TPST1))
- Andere Bezeichnung
- TPST1 (TPST1 Produkte)
- Synonyme
- MGC82552 Protein, MGC97723 Protein, R75054 Protein, Tango13a Protein, TANGO13A Protein, fj54g11 Protein, wu:fj54g11 Protein, tyrosylprotein sulfotransferase 1 Protein, tyrosylprotein sulfotransferase 1 L homeolog Protein, protein-tyrosine sulfotransferase 1 Protein, TPST1 Protein, tpst1.L Protein, tpst1 Protein, Tpst1 Protein
- Hintergrund
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Background: Protein-tyrosine sulfotransferase 1, also known as Tyrosylprotein sulfotransferase 1 and TPST1, is a single-pass type I I membrane protein which belongs to the protein sulfotransferase family. Tyrosine O-sulfation is a common posttranslational modification of proteins in all multicellular organisms. This reaction is mediated by a Golgi enzyme activity called tyrosylprotein sulfotransferase (TPST) that catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate to tyrosine residues within acidic motifs of polypeptides. Tyrosine O-sulfation has been shown to be important in protein-protein interactions in several systems. Tyrosine sulfation is mediated by one of two Golgi isoenzymes, called tyrosylprotein sulfotransferases (TPST-1 and TPST-2). A relatively small number of proteins are known to undergo tyrosine sulfation, including certain adhesion molecules, G-protein-coupled receptors, coagulation factors, serpins, extracellular matrix proteins, and hormones. TPST1 is a human tyrosylprotein sulfotransferase that uses 3'phosphoadenosine-5'phosphosulfate (PAPS) to transfer the sulfate moiety to proteins predominantly designated for secretion. TPST1 bears N-linked glycosyl residues exclusively at position Asn60 and Asn262. TPST1 and TPST2 have distinct biological roles that may reflect differences in their macromolecular substrate specificity.
Synonym: TANGO13A
- Molekulargewicht
- 41.7 kDa
- NCBI Accession
- NP_003587
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