GALE Protein (His tag)

Produktnummer ABIN7319157

Produktdetails

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses GALE Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human GALE Protein (His Tag)

Sequenz: Met 1-Ala348

Produktmerkmale: Recombinant Human UDP-Glucose 4-Epimerase is produced by our E.coli expression system and the target gene encoding Met1-Ala348 is expressed with a 6His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 50 mM TrisHCl, 150 mM NaCl, 2 mM DTT, 1 mM EDTA, pH 8.0.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Andere Bezeichnung: GALE (GALE Produkte)

Synonyme: GALE Protein, im:7147391 Protein, wu:fb05f01 Protein, zgc:136578 Protein, F15H21.11 Protein, F15H21_11 Protein, REB1 Protein, ROOT EPIDERMAL BULGER1 Protein, ROOT HAIR DEFECTIVE 1 Protein, UDP-GLUCOSE 4-EPIMERASE Protein, UGE4 Protein, ECK0748 Protein, galD Protein, JW0742 Protein, SMU.888 Protein, BA5505 Protein, BA5700 Protein, VFA0352 Protein, galE Protein, 2310002A12Rik Protein, AI323962 Protein, 1n569 Protein, xgale Protein, SDR1E1 Protein, UDP-galactose-4-epimerase Protein, NAD(P)-binding Rossmann-fold superfamily protein Protein, UDP-galactose 4-epimerase GalE Protein, UDP-glucose 4-epimerase Protein, UDP-glucose 4-epimerase GalE Protein, UDP-glucose/UDP-N-acetylglucosamine 4-epimerase Protein, galactose-4-epimerase, UDP Protein, UDP-galactose-4-epimerase L homeolog Protein, GALE Protein, gale Protein, RHD1 Protein, ECs0787 Protein, galE Protein, galE1 Protein, galE2 Protein, STY0809 Protein, galE-2 Protein, SG0897 Protein, galD Protein, Ent638_1250 Protein, Gale Protein, gale.L Protein

Hintergrund:

Background: The enzyme UDP-Glucose 4-Epimerase (GALE) is a homodimeric epimerase found in bacterial, plant and mammalian cells. UDP-Glucose 4-Epimerase performs the final step in the Leloir pathway of Galactose metabolism, it catalyzes two distinct but analogous reactions: the epimerization of UDP-Gglucose to UDP-Galactose and the epimerization of UDP-N-Acetylglucosamine to UDP-N-Acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids.

Synonym: UDP-Glucose 4-Epimerase, Galactowaldenase, UDP-Galactose 4-Epimerase, GALE

Molekulargewicht: 40.4 kDa

UniProt: Q14376

Pathways: Response to Water Deprivation, Cellular Glucan Metabolic Process