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VISTA Protein (His tag)

VISTA Spezies: Cynomolgus Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7320948
  • Target Alle VISTA Proteine anzeigen
    VISTA (V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA))
    Protein-Typ
    Recombinant
    Spezies
    • 6
    • 1
    Cynomolgus
    Quelle
    • 2
    • 2
    • 2
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses VISTA Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Cynomolgus VSIR Protein (His Tag)
    Sequenz
    Phe33-Ala194
    Produktmerkmale
    Recombinant Cynomolgus VSIR is produced by our Mammalian expression system and the target gene encoding Phe33-Ala194 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    VISTA (V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA))
    Andere Bezeichnung
    VSIR (VISTA Produkte)
    Synonyme
    MGC112715 Protein, MGC151567 Protein, B7-H5 Protein, B7H5 Protein, GI24 Protein, PP2135 Protein, SISP1 Protein, Dies1 Protein, VISTA Protein, V-set immunoregulatory receptor Protein, vsir Protein, Vsir Protein, VSIR Protein
    Hintergrund

    Background: platelet receptor Gi24 is a single-pass type I membrane protein, and located at the cell surface. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation. It is participated in the BMP signaling pathway. It also regulates the CD4-pasitive, alpha-beta T cell proliferation, and T cell cytokine production negatively. However, the protein can regulate stem cell differentiation positively.

    Synonym: Platelet receptor Gi24,Stress-induced secreted protein-1,Sisp-1,C10orf54,SISP1

    Molekulargewicht
    19.2 kDa
    UniProt
    A0A2K5UV12
    Pathways
    Cancer Immune Checkpoints
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