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Vitronectin Protein (VTN) (His tag)

VTN Spezies: Human Wirt: Human Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Produktnummer ABIN7319175
  • Target Alle Vitronectin (VTN) Proteine anzeigen
    Vitronectin (VTN)
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 11
    • 4
    • 1
    • 1
    • 1
    Human
    Quelle
    • 9
    • 4
    • 2
    • 2
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses Vitronectin Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Vitronectin/VTN Protein (His Tag)(Active)
    Sequenz
    Asp20-Leu478
    Produktmerkmale
    Recombinant Human Vitronectin is produced by our Mammalian expression system and the target gene encoding Asp20-Leu478 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Measured by the ability of the immobilized protein to support the adhesion of Jurkat cells.
    Top Product
    Discover our top product VTN Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Vitronectin (VTN)
    Andere Bezeichnung
    Vitronectin/VTN (VTN Produkte)
    Synonyme
    VTN Protein, DKFZp470F0511 Protein, LOC100228142 Protein, vtn Protein, zgc:112277 Protein, V75 Protein, VN Protein, VNT Protein, AI256434 Protein, Vn Protein, Aa1018 Protein, vitronectin Protein, vitronectin a Protein, vitronectin b Protein, vitronectin L homeolog Protein, VTN Protein, vtn Protein, vtna Protein, vtnb Protein, CpipJ_CPIJ016691 Protein, vtn.L Protein, Vtn Protein
    Hintergrund

    Background: Human Vitronectin/VTN is a cell adhesion and spreading factor. It can be found in the blood and the extracellular matrix (ECM). Vitronectin interacts with glycosaminoglycans and proteoglycans. The multimeric Vitronectin can efficiently bind to and incorporate into the ECM, Vitronectin can support cell adhesion through binding to various integrins and other proteoglycans. Vitronectin can be recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecular. It can as a inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Vitronectin contains an endogenous cleavage site, plus cleavage sites for elastase, thrombin, and plasmin.

    Synonym: Vitronectin, VN, S-Protein, Serum-Spreading Factor, V75, VTN

    Molekulargewicht
    53.4 kDa
    UniProt
    P04004
    Pathways
    Autophagie, Smooth Muscle Cell Migration
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