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CD86 Protein (CD86) (His tag)

CD86 Spezies: Rhesusaffen Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7320996
  • Target Alle CD86 Proteine anzeigen
    CD86
    Protein-Typ
    Recombinant
    Spezies
    • 21
    • 10
    • 5
    • 3
    • 3
    • 3
    Rhesusaffen
    Quelle
    • 23
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses CD86 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Rhesus macaque B7-2/CD86 Protein (His Tag)
    Sequenz
    Tyr31-Pro247
    Produktmerkmale
    Recombinant Rhesus macaque CD86 is produced by our Mammalian expression system and the target gene encoding Tyr31-Pro247 is expressed with a 6His tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD86 Protein
  • Kommentare

    40-90 kDa

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD86
    Andere Bezeichnung
    B7-2/CD86 (CD86 Produkte)
    Synonyme
    B7-2 Protein, B7.2 Protein, B70 Protein, CD28LG2 Protein, LAB72 Protein, B7 Protein, CLS1 Protein, Cd28l2 Protein, ETC-1 Protein, Ly-58 Protein, Ly58 Protein, MB7 Protein, MB7-2 Protein, TS/A-2 Protein, CD86 molecule Protein, CD86 antigen Protein, integrin subunit alpha 2b Protein, CD86 Protein, Cd86 Protein, Itga2b Protein
    Hintergrund

    Background: T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.

    Synonym: T-lymphocyte activation antigen CD86 isoform 1,Activation B7-2 antigen, CD86

    Molekulargewicht
    25.7 kDa
    UniProt
    H9ZFI8
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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