FGL1 Protein (His tag,Biotin)
-
- Target Alle FGL1 Proteine anzeigen
- FGL1 (Fibrinogen-Like 1 (FGL1))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
-
Spezies
- Human
-
Quelle
- Human Cells
- Aufreinigungstag / Konjugat
- Dieses FGL1 Protein ist gelabelt mit His tag,Biotin.
- Verwendungszweck
- Recombinant Human FGL1 (C-Avi-6His) Biotinylated
- Sequenz
- Leu23-Ile312
- Produktmerkmale
- Biotinylated Recombinant Human Fibrinogen-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu23-Ile312 is expressed with a Avi, 6His tag at the C-terminus.
- Reinheit
- >90 % as determined by reducing SDS-PAGE.
- Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human LAG-3-Fc(Cat#CU30) at 10μg/ml (100 μl/well) can bind Biotinylated Human FGL1-Avi(Cat#CY21). The ED50 of Human FGL1-Avi (Cat#CY21) is 1908ng/mL.
- Top Product
- Discover our top product FGL1 Protein
-
-
- Kommentare
-
35 kDa
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 300 mM NaCl, 10 % Glycerol, 2 mM EDTA, pH 8.0.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Target
- FGL1 (Fibrinogen-Like 1 (FGL1))
- Andere Bezeichnung
- FGL1 (FGL1 Produkte)
- Synonyme
- MGC84748 Protein, FGL1 Protein, DKFZp470A2333 Protein, Frep1 Protein, Lfire1 Protein, HFREP1 Protein, HP-041 Protein, LFIRE-1 Protein, LFIRE1 Protein, Mfire1 Protein, fibrinogen like 1 L homeolog Protein, fibrinogen like 1 Protein, fibrinogen-like 1 Protein, fibrinogen-like protein 1 Protein, fgl1.L Protein, FGL1 Protein, Fgl1 Protein
- Hintergrund
-
Background: Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.
Synonym: Fibrinogen-like protein 1, FGL1, HP-041, Hepassocin, HFREP-1, LFIRE-1
- Molekulargewicht
- 36.6 kDa
- UniProt
- Q08830
-