NKG2A & CD94 protein (Fc Tag)

Produktnummer ABIN7271623

Produktdetails

Target: NKG2A & CD94

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Fc Tag

Verwendungszweck: Mouse NKG2A&CD94 Protein, Fc Tag

Sequenz: Thr 95 - Ile 244 (NKG2A) & Ile 32 - Ile 179 (CD94)

Produktmerkmale: Mouse NKG2A&CD94, Fc Tag (NC4-M5254) is expressed from human 293 cells (HEK293). It contains AA Thr 95 - Ile 244 (NKG2A) & Ile 32 - Ile 179 (CD94) (Accession # Q9Z202-1 (NKG2A) & O54707-1 (CD94).

Reinheit: >95 % as determined by SDS-PAGE.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Applikationshinweise: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 61.3 kDa. The protein migrates as 70-80 kDa under reducing (R) condition due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: NKG2A & CD94

Andere Bezeichnung: NKG2A&CD94

Hintergrund: Synonyms:NKG2A & CD94,Description:CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 Molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

Molekulargewicht: 61.3 kDa