HLA-A*01:01 protein (SBP Tag)
Spezies: Human
Wirt: Mammalian Cells
Recombinant
> 80 %
BP, CP, ELISA, Neut
-
- Target
- HLA-A*01:01
- Protein-Typ
- Recombinant
- Spezies
- Human
-
Quelle
- Mammalian Cells
- Aufreinigungstag / Konjugat
- SBP Tag
- Applikation
- Blocking Peptide (BP), Control Peptide (CP), ELISA, Neutralization (Neut)
- Verwendungszweck
- The product is HLA-A*01:01 complexed with β2-microglobulin (b2m)
- Sequenz
-
heavy chain: GSHSMRYFFT SVSRPGRGEP RFIAVGYVDD TQFVRFDSDA ASQKMEPRAP WIEQEGPEYW DQETRNMKAH SQTDRANLGT LRGYYNQSED GSHTIQIMYG CDVGPDGRFL RGYRQDAYDG KDYIALNEDL RSWTAADMAA QITKRKWEAV HAAEQRRVYL EGRCVDGLRR YLENGKETLQ RTDPPKTHMT HHPISDHEAT LRCWALGFYP AEITLTWQRD GEDQTQDTEL VETRPAGDGT FQKWAAVVVP SGEEQRYTCH VQHEGLPKPL TLRWELSSQP TIPI
light chain: IQRTPKIQVY SRHPAENGKS NFLNCYVSGF HPSDIEVDLL KNGERIEKVE HSDLSFSKDW SFYLLYYTEF TPTEKDEYAC RVNHVTLSQP KIVKWDRDM
Sequences without tags. Tag location is at the discretion of the manufacturer. - Spezifität
- HLA-A*01:01 complexed with b2m, P04439 / P61769
- Produktmerkmale
- HLAs are produced in mammalian cell cultures as recombinant, truncated, soluble antigens, in complex with β2-microglobulin (HLA class I). As part of our quality control, all HLA are analyzed for purity by gel electrophoresis, concentration is determined by ELISA (0.5 mg/ml) and their functionality is verified with a specific antiserum.
- Aufreinigung
- Chromatography
- Reinheit
- > 80 %
- Endotoxin-Niveau
- Endotoxins have not been removed
-
-
- Applikationshinweise
- ELISA: 1 - 100 ng/mL
- Kommentare
-
sandwich ELISA, direct ELISA, bead ELISA, reactive with antibodies W6/32 and BBM.1 and specific antiserum, B cell ELI Spot (predicted), in vitro memory B cell stimulation (predicted), HLA competition assay (predicted), control in various assays (predicted)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- TRIS based buffer, pH 8.0, Sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 6 months
-
- Target
- HLA-A*01:01
- Hintergrund
- Human Leukozyte Antigen, human Antigen-presenting major histocompatibility complex class I (MHCI) molecule. Expressed on all cells, displays peptides to CD8-positive T cells. Involved in cellular immune response.
- Molekulargewicht
- approx. 50 kDa (38 kDa heavy chain + 12 kDa b2m)
- UniProt
- P04439
-
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