ACVA Protein (AA 311-426)
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- Target Alle ACVA Proteine anzeigen
- ACVA (Activin A (ACVA))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 311-426
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Verwendungszweck
- Human Activin A Protein
- Sequenz
- Gly311-Ser426
- Produktmerkmale
- Recombinant Human Activin A Protein is expressed from HEK293 without tag.It contains Gly311-Ser426.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product ACVA Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 4 mM HCI.
- Buffer
- Lyophilized from 0.22μm filtered solution in 4 mM HCI. Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ACVA (Activin A (ACVA))
- Andere Bezeichnung
- Activin A (ACVA Produkte)
- Synonyme
- inhibin beta A subunit Protein, Inhba Protein
- Hintergrund
- Activin-A, a member of the TGF-β superfamily, Extensive research over the past decades illuminated fundamental roles for activin-A in essential biologic processes, including embryonic development, stem cell maintenance and differentiation, haematopoiesis, cell proliferation and tissue fibrosis. Activin-A signals through two type I and two type II receptors which, upon ligand binding, activate their kinase activity, phosphorylate the SMAD2 and 3 intracellular signaling mediators that form a complex with SMAD4, translocate to the nucleus and activate or silence gene expression.
- Molekulargewicht
- 12.97 kDa. Due to glycosylation, the protein migrates to 14-15 kDa under reduced (R) condition, and 23-25 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.
- UniProt
- P08476
- Pathways
- Hormone Transport, Peptide Hormone Metabolism
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