CCL24 Protein (AA 27-119) (His tag)

Produktnummer ABIN7274047

Produktdetails

Target: CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))

Protein-Typ: Recombinant

Proteineigenschaft: AA 27-119

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CCL24 Protein ist gelabelt mit His tag.

Verwendungszweck: Human CCL24 Protein

Sequenz: Val27-Cys119

Produktmerkmale: Recombinant Human CCL24 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Val27-Cys119.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human CCL24, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Anti-CCL24 Antibody, hFc Tag with the EC50 of 26.9ng/ml determined by ELISA. See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl, 100 mM L-arginine ( pH 7.5). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))

Andere Bezeichnung: CCL24 (CCL24 Produkte)

Synonyme: Ckb-6 Protein, MPIF-2 Protein, MPIF2 Protein, SCYA24 Protein, CKb-6 Protein, Scya24 Protein, C-C motif chemokine ligand 24 Protein, chemokine (C-C motif) ligand 24 Protein, CCL24 Protein, Ccl24 Protein

Hintergrund: C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fibrosis. It was found to be significantly expressed in patients with non-alcoholic steatohepatitis, in whom it regulates profibrotic processes in the liver.

Molekulargewicht: 11.9 kDa. Due to glycosylation, the protein migrates to 20-25 kDa based on Tris-Bis PAGE result.

UniProt: O00175

Pathways: Regulation of Actin Filament Polymerization