CD37 Protein (AA 113-240) (Fc Tag)
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- Target Alle CD37 (TSPAN26) Proteine anzeigen
- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 113-240
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CD37 Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Human CD37 Protein
- Sequenz
- Ala113-Asn240
- Produktmerkmale
- Recombinant Human CD37 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ala113-Asn240.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product TSPAN26 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
- Andere Bezeichnung
- CD37 (TSPAN26 Produkte)
- Synonyme
- Tspan26 Protein, GP52-40 Protein, TSPAN26 Protein, CD37 antigen Protein, CD37 molecule Protein, Cd37 Protein, CD37 Protein
- Hintergrund
- CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and targeting this molecule may provide additional benefit to relapsed or refractory patients.
- Molekulargewicht
- 41.9 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
- Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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