CD70 Protein (AA 39-194) (His tag)
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- Target Alle CD70 Proteine anzeigen
- CD70 (CD70 Molecule (CD70))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 39-194
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Spezies
- Cynomolgus
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses CD70 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Cynomolgus CD27 Ligand/CD70 Protein
- Sequenz
- Gln39-Pro194
- Produktmerkmale
- Recombinant Cynomolgus CD27 Ligand/CD70 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Gln39-Pro194.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus CD27 Ligand, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Cynomolgus/Rhesus macaque CD27, hFc Tag with the EC50 of 41.5ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product CD70 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CD70 (CD70 Molecule (CD70))
- Andere Bezeichnung
- CD27 Ligand (CD70 Produkte)
- Synonyme
- CD27LG Protein, Cd27l Protein, Tnfsf7 Protein, CD27L Protein, TNFSF7 Protein, CD70 antigen Protein, CD70 molecule Protein, Cd70 molecule Protein, Cd70 Protein, CD70 Protein
- Hintergrund
- CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
- Molekulargewicht
- 18.4 kDa. Due to glycosylation, the protein migrates to 60-90 kDa based on Tris-Bis PAGE result.
- Pathways
- Cancer Immune Checkpoints
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