FGF10 Protein (AA 38-208)

Produktnummer ABIN7274614

Dieses Recombinant FGF10-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für FGF10 Protein (AA 38-208) (ABIN7274614)

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 90 % as determined by Tris-Bis PAGE

Produktdetails

Proteineigenschaft: AA 38-208

Verwendungszweck: Human FGF10 Protein

Sequenz: Gln38-Ser208

Produktmerkmale: Recombinant Human FGF10 Protein is expressed from E.coli without tag.It contains Gln38-Ser208.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 0.1 EU per μg by the LAL method.

Biological Activity Comment: The affinity constant of 0.299 nM as determined in SPR assay (Biacore T200). See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in 20 mM Tris, 150 mM NaCl ( pH 8.0). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Andere Bezeichnung: FGF10

Hintergrund: Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more susceptible to chronic disease.

Molekulargewicht: 19.3 kDa. The protein migrates to 25 kDa based on Tris-Bis PAGE result.

UniProt: O15520

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus