FGF10 Protein

Produktnummer ABIN7274614

Produktdetails

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Sequenz: Gln38-Ser208

Reinheit: > 90% as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Biological Activity Comment: The affinity constant of 0.299 nM as determined in SPR assay (Biacore T200). See testing image for detail.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in 20 mM Tris, 150 mM NaCl ( pH 8.0). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Andere Bezeichnung: FGF10 (FGF10 Produkte)

Synonyme: fgf10 Protein, fgf-10 Protein, wu:fd11d03 Protein, zgc:109774 Protein, FGF10 Protein, AEY17 Protein, BB213776 Protein, Fgf-10 Protein, Gsfaey17 Protein, FGF-10 Protein, fibroblast growth factor 10a Protein, fibroblast growth factor 10 Protein, fgf10a Protein, FGF10 Protein, fgf10 Protein, Fgf10 Protein

Hintergrund: FGF-10, KGF2,Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more susceptible to chronic disease.

Molekulargewicht: 19.3 kDa. The protein migrates to 25 kDa based on Tris-Bis PAGE result.

UniProt: O15520

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus