GPC1 Protein (AA 24-529) (His tag)
-
- Target Alle GPC1 Proteine anzeigen
- GPC1 (Glypican 1 (GPC1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 24-529
-
Spezies
- Maus
-
Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses GPC1 Protein ist gelabelt mit His tag.
- Verwendungszweck
- Mouse Glypican 1/GPC1 Protein
- Sequenz
- Asp24-Ser529
- Produktmerkmale
- Recombinant Mouse Glypican 1/GPC1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp24-Ser529.
- Reinheit
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterilität
- 0.22 μm filtered
- Endotoxin-Niveau
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product GPC1 Protein
-
-
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in 50 mM Tris,150 mM NaCl ( pH 7.5). Normally 8 % trehalose is added as protectant before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- GPC1 (Glypican 1 (GPC1))
- Andere Bezeichnung
- Glypican 1 (GPC1 Produkte)
- Synonyme
- gpc1 Protein, zgc:63947 Protein, GPC1 Protein, Glypican-1 Protein, glypican Protein, AI462976 Protein, HSPG M12 Protein, HSPGM12 Protein, glypican 1b Protein, glypican 1 Protein, gpc1b Protein, GPC1 Protein, gpc1 Protein, Gpc1 Protein
- Hintergrund
- CAR-T cells targeting glypican-1 (GPC1)-specific human and murine CAR-T cells generated from our original anti-human/mouse GPC1 antibody showed strong antitumor effects in xenogeneic and syngeneic mouse models, respectively. Importantly, the murine CAR-T cells enhanced endogenous T cell responses against a non-GPC1 tumor antigen through the mechanism of antigen-spreading and showed synergistic antitumor effects with anti-PD-1 antibody without any adverse effects in syngeneic models.
- Molekulargewicht
- 56.8 kDa. Due to glycosylation, the protein migrates to 65-68 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9QZF2
- Pathways
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation
-