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IL-10 Protein (His-Avi Tag)

IL10 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Produktnummer ABIN7274896
  • Target Alle IL-10 (IL10) Proteine anzeigen
    IL-10 (IL10) (Interleukin 10 (IL10))
    Protein-Typ
    Recombinant
    Spezies
    • 18
    • 13
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 33
    • 22
    • 15
    • 6
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses IL-10 Protein ist gelabelt mit His-Avi Tag.
    Sequenz
    Ser19-Asn178
    Reinheit
    > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 0.13 nM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product IL10 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    IL-10 (IL10) (Interleukin 10 (IL10))
    Andere Bezeichnung
    IL-10 (IL10 Produkte)
    Synonyme
    CSIF Protein, GVHDS Protein, IL-10 Protein, IL10A Protein, TGIF Protein, Il-10 Protein, IL10X Protein, interleukin 10 Protein, IL10 Protein, Il10 Protein
    Hintergrund
    Interleukin-10, IL-10, CSIF, IL10A, TGIF, B-TCGF, GVHDS, MGC126450, MGC126451,Interleukin 10 (IL10) is a key anti-inflammatory cytokine that can inhibit proinflammatory responses of both innate and adaptive immune cells. An association between IL10 and intestinal mucosal homeostasis became clear with the discovery that IL10 and IL10 receptor (IL10R)-deficient mice develop spontaneous intestinal inflammation. Similarly, patients with deleterious mutations in IL10, IL10RA, or IL10RB present with severe enterocolitis within the first months of life.
    Molekulargewicht
    21.3 kDa. Due to glycosylation, the protein migrates to 23-25 kDa based on Tris-Bis PAGE result.
    UniProt
    P22301
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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