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NOTCH3 Protein (His-Avi Tag)

NOTCH3 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Produktnummer ABIN7275366
  • Target Alle NOTCH3 Proteine anzeigen
    NOTCH3 (Notch 3 (NOTCH3))
    Protein-Typ
    Recombinant
    Spezies
    • 7
    • 1
    Human
    Quelle
    • 4
    • 3
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses NOTCH3 Protein ist gelabelt mit His-Avi Tag.
    Sequenz
    Ala40-Glu467
    Reinheit
    > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product NOTCH3 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    NOTCH3 (Notch 3 (NOTCH3))
    Andere Bezeichnung
    Notch 3 (NOTCH3 Produkte)
    Synonyme
    CADASIL Protein, CASIL Protein, IMF2 Protein, AW229011 Protein, N3 Protein, hpbk Protein, fa14b08 Protein, notch5 Protein, wu:fa14b08 Protein, notch 3 Protein, NOTCH3 Protein, Notch3 Protein, notch3 Protein
    Hintergrund
    CADASIL, Notch homolog 3, Notch-3, NOTCH3,Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular domain of transmembrane ligands Jagged, Delta, and Serrate expressed on the surface of a neighboring cell. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs
    Molekulargewicht
    47.7 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Tris-Bis PAGE result.
    UniProt
    Q9UM47
    Pathways
    Notch Signalweg
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