IgG1 Protein (Asp239Glu-Mutant, Cys103Ser-Mutant, Leu241Glu-Mutant)

Produktnummer ABIN7316859

Produktdetails

Target: IgG1

Protein-Typ: Recombinant

Proteineigenschaft: Asp239Glu-Mutant, Cys103Ser-Mutant, Leu241Glu-Mutant

Spezies: Human

Quelle: HEK-293 Cells

Verwendungszweck: Human IgG1 Fc (C103S, D239E, L241E) Protein, Tag Free (MALS verified)

Sequenz: Pro 100 - Lys 330

Produktmerkmale: Human IgG1 Fc (C103S, D239E, L241E), Tag Free is expressed from human 293 cells (HEK293). It contains AA Pro 100 - Lys 330 (Accession # P01857 (C103S, D239E, L241E).

Reinheit: 95,00 %

Endotoxin-Niveau: 1.0 EU per μg

Güteklasse: MALS verified

Anwendungsinformationen

Kommentare:

This protein carries no "tag". The protein has a calculated MW of 26 kDa. The protein migrates as 31-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: IgG1

Abstract: IgG1 Produkte

Synonyme: IgG1 Protein, Igh-4 Protein, VH7183 Protein, immunoglobulin heavy constant gamma 1 (G1m marker) Protein, Ighg1 Protein

Substanzklasse: Antibody

Hintergrund: Synonyms:IgG1,Description:Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.

Molekulargewicht: 26 kDa