IL12RB1 Protein (Biotin,His-Avi Tag)

Produktnummer ABIN7447938

Produktdetails

Target: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses IL12RB1 Protein ist gelabelt mit Biotin,His-Avi Tag.

Verwendungszweck: Biotinylated Human IL-12 R beta 1 / CD212 Protein, His,Avitag™ (MALS verified)

Sequenz: Cys 24 - Glu 540

Produktmerkmale: Biotinylated Human IL-12 R beta 1, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Cys 24 - Glu 540 (Accession # P42701-1).

Reinheit: 95,00 %

Endotoxin-Niveau: 1.0 EU per μg

Güteklasse: MALS verified

Anwendungsinformationen

Kommentare:

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 60.7 kDa. The protein migrates as 70-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Andere Bezeichnung: IL-12 R beta 1 (IL12RB1 Produkte)

Synonyme: Il12rb Protein, IL12RB1 Protein, IL-12R Protein, CD212 Protein, IL-12R-BETA1 Protein, IL12RB Protein, IL-12R[b] Protein, interleukin 12 receptor subunit beta 1 Protein, interleukin 12 receptor, beta 1 Protein, Il12rb1 Protein, IL12RB1 Protein

Hintergrund: Synonyms:IL-12 R beta 1,IL12RB1,CD212,IL12R,IL12RB,IL-12RB1,Description:The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

Molekulargewicht: 60.7 kDa

NCBI Accession: NP_005526

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation