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IL-37 Protein (AA 27-192)

IL37 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7454154
  • Target Alle IL-37 (IL37) Proteine anzeigen
    IL-37 (IL37) (Interleukin 37 (IL37))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 27-192
    Spezies
    Human
    Quelle
    • 6
    • 1
    • 1
    Escherichia coli (E. coli)
    Verwendungszweck
    Human IL-37 Protein
    Sequenz
    Lys27-Asp192
    Produktmerkmale
    Recombinant Human IL-37 Protein is expressed from E.coli without tag.It contains Lys27-Asp192.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    The affinity constant of 0.12 μM as determined in SPR assay (Biacore T200). See testing image for detail.
    Top Product
    Discover our top product IL37 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in 20 mM PBS, 2 mM DTT ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Konservierungsmittel
    Dithiothreitol (DTT)
    Vorsichtsmaßnahmen
    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    IL-37 (IL37) (Interleukin 37 (IL37))
    Andere Bezeichnung
    IL-37 (IL37 Produkte)
    Synonyme
    FIL1 Protein, FIL1(ZETA) Protein, FIL1Z Protein, IL-1F7 Protein, IL-1H Protein, IL-1H4 Protein, IL-1RP1 Protein, IL-37 Protein, IL1F7 Protein, IL1H4 Protein, IL1RP1 Protein, interleukin 37 Protein, IL37 Protein
    Hintergrund
    IL-37 is a unique member of the IL-1 family of cytokines, which functions as a natural suppressor of inflammatory and immune responses. Immune and non-immune cells produce IL-37 precursor following pro-inflammatory stimuli. Following activating cleavage by caspase-1, mature IL-37 translocates to the nucleus, where it suppresses transcription of pro-inflammatory genes.
    Molekulargewicht
    18.55 kDa same as Tris-Bis PAGE result.
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