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HLA-A*24:02 (Monomer) protein (Biotin,Survivin 2B)

Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Produktnummer ABIN7454356
  • Target
    HLA-A*24:02
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Monomer
    Spezies
    Human
    Quelle
    • 9
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Biotin,Survivin 2B
    Verwendungszweck
    Biotinylated Human HLA-A*24:02 & B2M & Survivin 2B (AYACNTSTL) Monomer Protein
    Sequenz
    Gly25-Thr305 (HLA-A*24:02), Ile21-Met119 (B2M) and AYACNTSTL peptide
    Spezifität
    Uni-Prot: AAA59600.1 (HLA-A*24:02), P61769 (B2M), AYACNTSTL
    Produktmerkmale
    Recombinant Biotinylated Human HLA-A*24:02 & B2M & Survivin 2B (AYACNTSTL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*24:02), Ile21-Met119(B2M) and AYACNTSTL peptide.
    Reinheit
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    HLA-A*24:02
    Hintergrund
    Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus.
    Molekulargewicht
    50.20 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
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