HLA-A*24:02 (Monomer) protein (Biotin,Survivin 2B)

Produktnummer ABIN7454356

Produktdetails

Target: HLA-A*24:02

Protein-Typ: Recombinant

Proteineigenschaft: Monomer

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Biotin,Survivin 2B

Verwendungszweck: Biotinylated Human HLA-A*24:02 & B2M & Survivin 2B (AYACNTSTL) Monomer Protein

Sequenz: Gly25-Thr305 (HLA-A*24:02), Ile21-Met119 (B2M) and AYACNTSTL peptide

Spezifität: Uni-Prot: AAA59600.1 (HLA-A*24:02), P61769 (B2M), AYACNTSTL

Produktmerkmale: Recombinant Biotinylated Human HLA-A*24:02 & B2M & Survivin 2B (AYACNTSTL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*24:02), Ile21-Met119(B2M) and AYACNTSTL peptide.

Reinheit: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: HLA-A*24:02

Hintergrund: Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus.

Molekulargewicht: 50.20 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.