F2RL1 Protein (AA 37-71) (Fc Tag)

Produktnummer ABIN7491171

Produktdetails

Target: F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 37-71

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses F2RL1 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant human F2RL1 protein with C-terminal human Fc tag

Spezifität: F2RL1 (Ser37-Gly71) hFc (Glu99-Ala330)

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))

Andere Bezeichnung: F2RL1 (F2RL1 Produkte)

Synonyme: par2 Protein, GPR11 Protein, PAR2 Protein, Gpcr11 Protein, PAR-2 Protein, Par2 Protein, Par-2 Protein, Proteinase-activated receptor 2 Protein, F2R like trypsin receptor 1 Protein, coagulation factor II (thrombin) receptor-like 1 Protein, par2 Protein, F2RL1 Protein, F2rl1 Protein

Hintergrund: This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity. [provided by RefSeq, Jun 2016]

Molekulargewicht: predicted molecular mass of 29.7 kDa after removal of the signal peptide. The apparent molecular mass of F2RL1-hFc is 33-53 kDa due to glycosylation.

UniProt: P55085

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interaktom