Prokineticin Receptor 1 Protein (PROKR1) (AA 1-62) (Fc Tag)
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- Target Alle Prokineticin Receptor 1 (PROKR1) Proteine anzeigen
- Prokineticin Receptor 1 (PROKR1)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-62
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Prokineticin Receptor 1 Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Recombinant Human PROKR1 Protein with C-terminal human Fc tag
- Spezifität
- PROKR1 (Met1-Lys62) hFc (Glu99-Ala330)
- Produktmerkmale
- Extracellular Domain Protein
- Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
- Reinheit
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
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- Target
- Prokineticin Receptor 1 (PROKR1)
- Andere Bezeichnung
- PROKR1 (PROKR1 Produkte)
- Synonyme
- EG-VEGFR1 Protein, Gpr73 Protein, Pkr1 Protein, GPR73 Protein, GPR73a Protein, PKR1 Protein, ZAQ Protein, PROKR1 Protein, prokineticin receptor 1 Protein, Prokr1 Protein, PROKR1 Protein
- Hintergrund
- This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016]
- Molekulargewicht
- predicted molecular mass of 33.1 kDa after removal of the signal peptide. The apparent molecular mass of PROKR1-hFc is 35-70 kDa due to glycosylation.
- UniProt
- Q8TCW9
- Pathways
- Hedgehog Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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