ACVR1C/ALK7 Protein (AA 22-113) (Fc Tag)
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- Target Alle ACVR1C/ALK7 (ACVR1C) Proteine anzeigen
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 22-113
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses ACVR1C/ALK7 Protein ist gelabelt mit Fc Tag.
- Verwendungszweck
- Recombinant Human ACVR1C Protein with C-terminal human Fc tag
- Spezifität
- ACVR1C (Leu22-Glu113) hFc (Glu99-Ala330)
- Produktmerkmale
- Extracellular Domain Protein
- Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
- Reinheit
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product ACVR1C Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
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- Target
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- Andere Bezeichnung
- ACVR1C (ACVR1C Produkte)
- Synonyme
- ACVRLK7 Protein, ALK7 Protein, Alk-7 Protein, C230097P10 Protein, Alk7 Protein, habrec1 Protein, activin A receptor type 1C Protein, activin A receptor, type IC Protein, ACVR1C Protein, Acvr1c Protein
- Hintergrund
- ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
- Molekulargewicht
- predicted molecular mass of 36.0 kDa after removal of the signal peptide. The apparent molecular mass of ACVR1C-hFc is 35-70 kDa due to glycosylation.
- UniProt
- Q8NER5
- Pathways
- Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
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