GPRC5D Protein
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- Target Alle GPRC5D Proteine anzeigen
- GPRC5D (G Protein-Coupled Receptor, Family C, Group 5, Member D (GPRC5D))
- Protein-Typ
- Synthetic Nanodisc
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Verwendungszweck
- Human GPRC5D full length protein-synthetic nanodisc
- Produktmerkmale
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product GPRC5D Protein
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- Kommentare
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Haltbarkeit
- 12 months
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- Target
- GPRC5D (G Protein-Coupled Receptor, Family C, Group 5, Member D (GPRC5D))
- Andere Bezeichnung
- GPRC5D (GPRC5D Produkte)
- Synonyme
- GPRC5D Protein, RGD1563887 Protein, G protein-coupled receptor class C group 5 member D Protein, G protein-coupled receptor, class C, group 5, member D Protein, G protein-coupled receptor, family C, group 5, member D Protein, GPRC5D Protein, Gprc5d Protein
- Hintergrund
- The protein encoded by this gene is a member of the G protein-coupled receptor family. Recent studies demonstrate that GPRC5D is expressed on malignant bone marrow plasma cells, whereas normal tissue expression is limited to the hair follicle. It may represent a potential target for effector-cell-mediated therapy to treat plasma-cell disorders like MM.
- Molekulargewicht
- The human full length GPRC5D Protein has a MW of 38.6 kDa
- UniProt
- Q9NZD1
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