TM4SF1 Protein

Produktnummer ABIN7491747

Produktdetails

Target: TM4SF1 (Transmembrane 4 L Six Family Member 1 (TM4SF1))

Protein-Typ: Synthetic Nanodisc

Spezies: Human

Quelle: HEK-293 Cells

Verwendungszweck: Human TM4SF1 full length protein-synthetic nanodisc

Produktmerkmale: Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Anwendungsinformationen

Kommentare:

Advantages of Synthetic Nanodiscs:

• Highly purified membrane proteins
• High solubility in aqueous solutions
• High stability
• Proteins are in a native membrane environment and remain biologically active
• No detergent and can be used for cell-based assays
• No MSP backbone proteins

Limitations of Synthetic Nanodiscs:

• Intolerant to acids and high concentrations of divalent metal ions

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: TM4SF1 (Transmembrane 4 L Six Family Member 1 (TM4SF1))

Andere Bezeichnung: TM4SF1 (TM4SF1 Produkte)

Synonyme: MGC85546 Protein, h-l6 Protein, m3s1 Protein, taal6 Protein, H-L6 Protein, L6 Protein, M3S1 Protein, TAAL6 Protein, MM3 Protein, M3s1 Protein, transmembrane 4 L six family member 1 Protein, transmembrane 4 L six family member 1 S homeolog Protein, transmembrane 4 superfamily member 1 Protein, TM4SF1 Protein, tm4sf1.S Protein, tm4sf1 Protein, Tm4sf1 Protein

Hintergrund: The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas.

Molekulargewicht: The human full length TM4SF1 protein has a MW of 21.6 kDa

UniProt: P30408